During the COVID-19 pandemic, many art historians have reframed their work to address issues of health and medicine. For others, the attendant isolation and lack of mobility associated with this crisis have led them to reexamine their intellectual approaches. Authored by five leading art historians who have published on the subjects of art, medicine, and health, the responses that follow reflect on the questions: How have we attempted to make sense of the pandemic experience with a view to the histories we study? In what ways might the recent health crisis be better framed in terms of the tribulations of health and medicine of the past?